Jon Heder stars as Drex Greene, a regular college grad who finds himself undergoing an inexplicable transformation that begins when he wakes up at the bottom of a water filled bathtub. Drex’s room-mate Matt, who has been eagerly filming his demise, informs him that he’s easily (and inhumanly) been underwater for more than half-hour.
As he starts to develop zombie-like tendencies, Drex enlists the help of his two friends, Cassie and Matt, to help him uncover the truth about the peculiar changes he is experiencing. In the process, Drex meets his match – an exotic beauty named Aurora – who may hold the answers to Drex’s many questions. Drex must decipher whether he really is a zombie, like Matt is convinced he is, or whether he’s something entirely different.
Josh Gad stars as Matt, who is determined to profit from his friend’s changes and Krysten Ritter stars as Cassie, a beautiful young med student whose curiosity fuels a powerful interest in Drex's new condition. Wayne Knight appears as Andy Batten, Drex’s nosy co-worker, who is determined to create trouble in Drex’s career.
Woke Up Dead consists of 22 five minute episodes.